产品货号:
Z35555
中文名称:
PLK1抗体
英文名称:
Anti-PLK1 Antibody (Clone#6D11)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PLK1 Antibody (Clone#6D11) |
指标别名 | PLK;PLK 1;PLK1;Polo like kinase 1;STPK13 |
克隆性 | Monoclonal |
检验物种 | human,monkey |
应用范围 | WB |
基因名称 | PLK1 |
克隆号 | 6D11 |
抗体来源 | Mouse |
抗体类型 | IgG2b |
免疫原 | E.coli-derived human PLK1 recombinant protein (Position:K86-N430).Human PLK1 shares 95.4% and 96.2% amino acid (aa) sequence identity with mouse and rat PLK1,respectively. |
实际分子量 | 68KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | protein G purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Serine/threonine-protein kinase PLK1,also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13(STPK13),is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene.Plk1 is an early trigger for G2/M transition.It supports the functional maturation of the centrosome in late G2/early prophaseand establishment of the bipolar spindle.Also,Plk1 phosphorylates and activates cdc25C,a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex.Studies have shown that the loss of PLK1 expression can inducepro-apoptotic pathways and inhibit growth.Based on yeast and murine studies of meiosis,human PLK1 may also have a regulatory function in meiosis. |
Uniprot ID | P53350 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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